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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Topoisomerase

Request The Product List ofTopoisomerase Topoisomerase

Cat. No. Product Name Information
PC-22736

Pixantrone

Topo II inhibitor, MCM2 inhibitor

Pixantrone (BBR2778) dimaleate is a topoisomerase II inhibitor and DNA intercalator with anti-tumor activity, also is a direct mini-chromosome maintenance protein 2 (MCM2) inhibitor, induces cell cycle arrest and apoptosis in ovarian cancer cells via targeting MCM2.
PC-22289

Epirubicin hydrochloride

Foxp3 inhibitor, Topo inhibitor

Epirubicin hydrochloride (4'-Epidoxorubicin hydrochloride) is a semisynthetic L-arabino derivative of doxorubicin with antineoplastic agent by inhibiting topoisomerase, also is a forkhead box protein 3 (FOXP3) inhibitor.
PC-22288

Genz-644282

Topo I inhibitor

Genz-644282 is a potent, non-camptothecin topoisomerase I (Top1) inhibitor, shows potent activities against a panel of human tumor cell lines with IC50 of 1.8 nM-1.8 uM.

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