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Camptothecin

Chemical Structure : Camptothecin

CAS No.: 7689-03-4

Camptothecin (Campathecin, (S)-(+)-Camptothecin, CPT)

货号: PC-27848Not For Human Use, Lab Use Only.

Camptothecin (CPT) is a kind of alkaloid and potent specific DNA topoisomerase I (Topo I) inhibitor with IC50 of 679 nM, exhibits broad antineoplastic activity against multiple cancers.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Camptothecin (CPT) is a kind of alkaloid and potent specific DNA topoisomerase I (Topo I) inhibitor with IC50 of 679 nM, exhibits broad antineoplastic activity against multiple cancers.

物理化学性质&存储条件

分子量 348.36
分子式 C20H16N2O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-4-Ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

参考文献

1. Luzzio MJ, et al. J Med Chem. 1995 Feb 3;38(3):395-401.

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