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Betulinic acid

Chemical Structure : Betulinic acid

CAS No.: 472-15-1

Betulinic acid (Lupatic acid;Betulic acid)

货号: PC-42639Not For Human Use, Lab Use Only.

Betulinic acid (Betulic acid) is a naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Betulinic acid (Betulic acid) is a naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties.
Betulinic acid shows to be a catalytic inhibitor of Topo II with IC50 values ranging from 0.38 to 58 uM.
Betulinic acid induces cell death through induction of apoptosis and inhibition of autophagic flux in microglia BV-2 cells.

物理化学性质&存储条件

分子量 456.7003
分子式 C30H48O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3β)-

参考文献

1. Potze L, et al. Cell Death Dis. 2014 Apr 10;5:e1169.

2. Seo J, et al. Biomol Ther (Seoul). 2017 Mar 10. doi: 10.4062/biomolther.2016.255.

3. Wada S, et al. Chem Biodivers. 2005 May;2(5):689-94.

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