| Cat. No. |
Product Name |
Information |
| PC-20362 |
QRX-431
TRβ1 agonist
|
QRX-431 (Thyromimetic GC-1, Sobetirome, QRX431) is a TRβ1-selective thyromimetic, selectively binds to TRβ over TRα with Kd values of 0.1 and 1.8 nM, respectively. |
| PC-20361 |
CS27109
THR-β agonist
|
CS27109 is a potent, selective thyroid hormone receptor-β (THR-β) agonist with AC50 value of 1.98 uM, 12.6-fold selectivity over THR-α. |
| PC-38128 |
DCZ0415
TRIP13 inhibitor
|
DCZ0415 (DCZ-0415) is a small-molecule inhibitor targeting thyroid hormone receptor interacting protein 13 (TRIP13) with Kd of 2.42 uM in SPR assay. |
| PC-38030 |
VK2809
THRβ agonist
|
VK2809 (VK-2809, MB-07811) is a potent, liver-specific thyroid hormone receptor β (THRβ) agonist for development for the treatment of hypercholesterolemia. |
| PC-35610 |
KB-141
THR-β agonist
|
KB-141 (KB141) is a potent, selective thyroid hormone receptor TRβ (THR-β) agonist (IC50=1.1 nM), binds to hTRβ with a 14-fold higher affinity than to hTRα. |
| PC-42920 |
MGL-3196
THR-β agonist
|
MGL-3196 (VIA-3196, Resmetirom) is a potent and highly selective agonist of THR-β (Thyroid Hormone Receptor β) with EC50 of 0.21 uM. |
| PC-22997 |
ALG-055009
THRβ agonist
|
ALG-055009 is a potent, selective thyroid hormone receptor β (THR-β) agonist with EC50 of 63 nM, 5.7 fold selective over THR-α. |
| PC-22746 |
DCZ5418
TRIP13 inhibitor
|
DCZ5418 is a specific small molecule inhibitor of thyroid hormone receptor interacting protein 13 (TRIP13), shows anti-multiple myeloma activity in vitro and in vivo. |
| PC-22745 |
TRIP13 inhibitor TI17
TRIP13 inhibitor
|
TI17 is a specific small molecule inhibitor of thyroid hormone receptor interacting protein 13 (Trip13), effectively inhibits the proliferation and induces the cycle arrest and apoptosis of MM cells. |
