| Cat. No. |
Product Name |
Information |
| PC-61382 |
Licogliflozin
SGLT1/2 inhibitor
|
Licogliflozin (LIK066) is a novel sodium glucose transporter type 1 and type 2 (SGLT1/2) inhibitor for the oral treatment of type 2 diabetes. |
| PC-61130 |
HSK0935
SGLT2 inhibitor
|
HSK0935 is a potent and highly selective SGLT2 inhibitor with IC50 of 1.3 nM, >800-fold selectivity over SGLT1 (IC50>1 uM). |
| PC-60987 |
YM543
SGLT2 inhibitor
|
YM543 is a potent, selective and orally active SGLT2 inhibitor with IC50 of 8.9 nM, 280-fold selectivity over SGLT1. |
| PC-60689 |
LX2761
SGLT1/2 inhibitor
|
LX2761 is a potent, locally acting and orally bioavailable SGLT1 inhibitor that inhibits human SGLT1- and SGLT2-mediated glucose uptake with IC50 of 2.2 nM and 2.7 nM, respectively, restricted to the intestinal lumen. |
| PC-42592 |
Dapagliflozin
SGLT2 inhibitor
|
Dapagliflozin (BMS-512148) is a potent, selective, orally active hSGLT2 inhibitor with EC50 of 1.12 nM. |
| PC-44486 |
Sotagliflozin
SGLT1/SGLT2 inhibitor
|
Sotagliflozin (LX4211) is a potent, selective, dual SGLT1/SGLT2 inhibitor with IC50 of 14 nM for hSGLT2. |
| PC-45385 |
Bexagliflozin
SGLT2 inhibitor
|
Bexagliflozin (THR-1442, EGT1442) is a potent and selective SGLT2 inhibitor with IC50 of 2 nM. |
| PC-44436 |
PF-04971729
SGLT2 inhibitor
|
Ertugliflozin (PF-04971729) is a potent and selective SGLT2 inhibitor with IC50 of 0.877 nM for hSGLT2. |
| PC-42594 |
Canagliflozin
SGLT2 inhibitor
|
Canagliflozin (JNJ 28431754) is a highly potent and selective SGLT2 inhibitor with IC50 of 4.4, 3.7 and 2.0 nM for hSGLT2, rSGLT2 and mSGLT2, respectively. |
| PC-44115 |
Ipragliflozin
SGLT2 inhibitor
|
Ipragliflozin (ASP1941) is a highly potent and selective SGLT2 inhibitor with IC50 of 14 nM for hSGLT2. |
| PC-22576 |
Empagliflozin
SGLT2 inhibitor
|
Empagliflozin (BI-10773) is a potent, selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with IC50 of 3.1 nM (hSGLT-2), has a high degree of selectivity over SGLT-1, 4, 5 and 6, has potential for the oral treatment of type 2 diabetes mellitus (T2DM). |
| PC-42593 |
Dapagliflozin (2S)-1,2-propanediol hydrate
|
A potent, selective, orally active hSGLT2 inhibitor with EC50 of 1.12 nM. |
