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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-Ribosomal S6 Kinase (RSK)

Request The Product List ofRibosomal S6 Kinase (RSK) Ribosomal S6 Kinase (RSK)

Cat. No. Product Name Information
PC-25304

NSYSU-115

RSK2 inhibitor

NSYSU-115 is a highly potent, selective RSK2 inhibitor with IC50 of 45.5 nM.
PC-21764

BIX 02565

RSK2 inhibitor

BIX 02565 is a potent, selective ribosomal S6 kinase 2 (RSK2) inhibitor with IC50 of 1.1 nM.
PC-49024

PF-4708671

S6K1 inhibitor

PF-4708671 is a potent, specific, cell-permeable inhibitor of S6K1 (p70 ribosomal S6 kinase 1), inhibits the activity of full-length S6K1 in vitro with Ki of 20 nM, and S6K1 isolated from IGF1-stimulated HEK293 cells with IC50 of 160 nM.
PC-72701

S6K2 inhibitor Compound 2

S6K2 inhibitor

S6K2 inhibitor Compound 2 (S6K2-IN-1) is the first potent and highly isoform-specific S6K2 inhibitor with IC50 of 22 nM, inactive for the closely related isoform S6K1 at 5 uM.
PC-72284

PMD-026

RSK inhibitor

PMD-026 (PMD026) is an oral, reversible small molecule inhibitor of ribosomal S6 kinases (RSK1-4) with IC50 of 2 nM (RSK1), 0.7 nM (RSK2), 0.9 nM (RSK3) and 2 nM (RSK4).
PC-43060

LY-2584702 hydrochloride

p70S6K1 inhibitor

LY2584702 is a potent, selective, ATP-competitive inhibitor of P70S6 kinase-1 (p70S6K1) with IC50 of 4 nM.
PC-43059

LY2584702 tosylate

p70S6K1 inhibitor

LY2584702 tosylate is a potent, selective, ATP-competitive inhibitor of P70 S6 kinase-1 (p70S6K1) with IC50 of 4 nM.
PC-43058

LY2584702

p70S6K1 inhibitor

LY2584702 is a potent, selective, ATP-competitive inhibitor of P70 S6 kinase-1 (p70S6K1) with IC50 of 4 nM.
PC-62854

RSK2-IN-20

RSK2 inhibitor

RSK2-IN-20 is a potent, selective, and durable inhibitpr of RSK2 with IC50 of 47 nM.
PC-62045

BRD7389

RSK inhibitor

BRD7389 is an inhibitor of ribosomal S6 kinases (RSK) with IC50 of 1.5 uM, 2.4 uM, and 1.2 uM for RSK1, RSK2, and RSK3, respectively.
PC-60433

M2698

p70S6K/Akt inhibitor

M2698 (MSC2363318A) is a potent, selective, ATP-competitive, orally bioavailable and brain penetrant dual inhibitor of p70S6K and Akt1/3 with IC50 of 1 nM and 17 nM, respectively.
PC-70183

SL0101

RSK inhibitor

SL0101 (SL 0101-1) is the first specific inhibitor of RSK (p90 ribosomal S6 kinase) with IC50 of 89 nM for RSK2.

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