| Cat. No. |
Product Name |
Information |
| PC-45678 |
LJI308
RSK inhibitor
|
LJI308 (LJI 308) is a potent and specific pan-RSK inhibitor with IC50s of 6 nM, 4 nM and 13 nM for RSK1, RSK2 and RSK3 respectively. |
| PC-45677 |
LJH685
RSK inhibitor
|
LJH685 (LJH-685) is a potent and specific pan-RSK inhibitor with IC50s of 6 nM,5 nM and 4 nM for RSK1, RSK2 and RSK3 respectively. |
| PC-45919 |
CMK
RSK2 inhibitor
|
CMK is an irreversible inhibitor of the CTD of RSK2 with similar potency as Fmk, also potently inhibits a Fyn mutant in which Val285 was replaced with Cys (IC50=1 nM). |
| PC-45920 |
FMK
RSK inhibitor
|
FMK is an irreversible inhibitor of the CTD of RSK1 and RSK2 with IC50 of 15 nM for wt RSK2. |
| PC-42627 |
BI-D1870
RSK inhibitor
|
BI-D1870 is a potent, specific ATP-competitive inhibitor of RSK isoforms with IC50 of 10-30 nM for RSK1/2/3/4. |
| PC-27207 |
RSK2 inhibitor M39
RSK2 inhibitor
|
RSK2 inhibitor M39 is a high affinity, cell-active RSK2 inhibitor with SPR Kd value of 156 nM, inhibits the catalytic activity of RSK2 by suppressing YB1 phosphorylation and shows strong anti-tumor activity. |