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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-Ribosomal S6 Kinase (RSK)-CMK
CMK

Chemical Structure : CMK

CAS No.: 821794-90-5

CMK (RSK2 inhibitor CMK)

货号: PC-45919Not For Human Use, Lab Use Only.

CMK is an irreversible inhibitor of the CTD of RSK2 with similar potency as Fmk, also potently inhibits a Fyn mutant in which Val285 was replaced with Cys (IC50=1 nM).

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10 mg ¥2280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CMK is an irreversible inhibitor of the CTD of RSK2 with similar potency as Fmk, also potently inhibits a Fyn mutant in which Val285 was replaced with Cys (IC50=1 nM).

物理化学性质&存储条件

分子量 358.8221
分子式 C18H19ClN4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Ethanone, 1-[4-amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-chloro-

参考文献

1. Cohen MS, et al. Science. 2005 May 27;308(5726):1318-21.

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