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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-Ribosomal S6 Kinase (RSK)-RSK2 inhibitor M39
RSK2 inhibitor M39

Chemical Structure : RSK2 inhibitor M39

CAS No.: 362000-49-5

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RSK2 inhibitor M39

货号: PC-27207Not For Human Use, Lab Use Only.

RSK2 inhibitor M39 is a high affinity, cell-active RSK2 inhibitor with SPR Kd value of 156 nM, inhibits the catalytic activity of RSK2 by suppressing YB1 phosphorylation and shows strong anti-tumor activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

RSK2 inhibitor M39 is a high affinity, cell-active RSK2 inhibitor with SPR Kd value of 156 nM, inhibits the catalytic activity of RSK2 by suppressing YB1 phosphorylation and shows strong anti-tumor activity.

物理化学性质&存储条件

分子量 429.50
分子式 C22H19N7OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6-(((1H-benzo[d]imidazol-2-yl)thio)methyl)-2-((4,7-dimethylquinazolin-2-yl)amino)pyrimidin-4(3H)-one

参考文献

1. Feng N, et al. ChemMedChem. 2026 Jun 26;21(12):e70293.

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