Receptor Interacting Protein Kinase (RIPK) compound (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofReceptor Interacting Protein Kinase (RIPK) Receptor Interacting Protein Kinase (RIPK)

Cat. No.	Product Name	Information
PC-45564	WEHI-345 RIPK2 inhibitor	WEHI-345 is a potent and selective RIPK2 inhibitor with IC50/Kd of 130/46 nM.
PC-42301	RIPA-56 RIPK1 inhibitor	RIPA-56 is a highly potent, selective, stable Receptor-interacting protein kinase 1 (RIPK1, RIP1) inhibitor with IC50 of 13 nM.
PC-42065	GSK-481 RIPK1 inhibitor	GSK-481 (GSK481) is a highly potent, monokinase selective and ATP-competitive inhibitor of RIP1 kinase (RIPK1) with biochemical IC50 of 10 nM.
PC-26869	LT-1339-553 RIPK1 inhibitor	LT-1339-553 is a potent, selective and oral bioavailable RIPK1 inhibitor with IC50 of 4.32 nM, cellular antinecroptotic activity (EC50=14.43 nM).
PC-26713	SZM594 RIPK1/3 inhibitor	SZM594 (SZM-594) is a highly potent, dual inhibitor of RIPK1 and RIPK3 (RIPK1/3) with IC50 of 97 nM and 77 nM respectively, inhibits TSZ‐induced necroptosis in HT‐29 cells with EC50 of 0.17 uM.
PC-26020	WJH-C19 RIPK1 inhibitor	WJH-C19 is a novel potent, selective RIPK1 inhibitor with IC50 of 5.7 nM, shows negligible PI3Kα and RIPK2/3.
PC-25543	RIPK1 inhibitor 3-47 RIPK1 inhibitor	RIPK1 inhibitor 3-47 is a specific, allosteric small molecule inhibitor of RIPK1, effectively reduces phosphorylation of RIPK1 at 12 nM in WB assays (human NP cells), protects viability of TNF-α-treated NP cells.
PC-25227	Compound RP20 RIPK2 inhibitor	Compound RP20 is a potent, selective RIPK2 inhibitor with IC50 of 13 nM, does not inhibit RIPK1.
PC-24512	SZM-1209 RIPK1 inhibitor	SZM-1209 is a potent, specific RIPK1 inhibitor with Kd value of 85 nM, >100-fold selective over RIPK3, exhibits anti-necroptosis activity against human HT-29 cells with EC50 of 22.4 nM.
PC-24511	SIR1-365 RIPK1 inhibitor	SIR1-365 is a highly potent, selective, and metabolically stable allosteric kinase inhibitor of RIPK1.
PC-24510	RIPK1 inhibitor 13c RIPK1 inhibitor	RIPK1 inhibitor 13c is a potent, selective RIPK1 inhibitor with IC50 of 59.8 nM and Kd of 3.5 nM, effectively prevented the necroptosis (HT-29, EC50=4.58 nM) by inhibiting phosphorylation of RIPK1/RIPK3/MLKL single pathway.
PC-23024	Citronellol RIPK1 agonist	Citronellol is an orally active inducer of apoptosis and RIPK1 agonist.

PREV 1 2 3 456 NEXT