Receptor Interacting Protein Kinase (RIPK) compound (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofReceptor Interacting Protein Kinase (RIPK) Receptor Interacting Protein Kinase (RIPK)

Cat. No.	Product Name	Information
PC-22669	Nec-1s Necroptosis inhibitor, RIPK1 inhibitor	Nec-1s (7-Cl-O-Nec-1) is an optimized derivative of Nec-1 and potent, specific necroptosis inhibitor with EC50 of 210 nM in Jurkat cells, exhibits the protection in an ischemic brain injury model, selectively inhibits RIPK1 and lacks activity against IDO.
PC-22668	Necrostatin-5 Necroptosis inhibitor, RIPK1 inhibitor	Necrostatin-5 (Nec-5) is a potent, specific necroptosis inhibitor with EC50 of 240 nM in Jurkat cells, selectively and allosterically inhibits RIP1 kinase (RIPK-1).
PC-22667	Necrostatin-1 Necroptosis inhibitor, RIPK1 inhibitor	Necrostatin-1 (Nec-1) is a potent, specific and BBB-permeable necroptosis inhibitor with EC50 of 490 nM in Jurkat cells, selectively and allosterically inhibits RIP1 kinase (RIPK-1) with EC50 of 182 nM.
PC-21707	RIPK1 inhibitor 62 RIPK1 inhibitor	RIPK1 inhibitor 62 is a potent, selective, orally bioavailable type-II kinase inhibitor of RIPK1 with IC50 of 3.5 nM (hRIPK1), 200-fold less potent against hRIPK3.
PC-20562	aYM155 YM155 prodrug	aYM155 is a brain-penetrating prodrug form of YM155 (Cat. PC-42439, potent survivin inhibitor), displays potent cell killing activity against a broad panel of patient-derived GBM cancer stem-like cells (IC50=0.7-10 nM).

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