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RIPA-56

Chemical Structure : RIPA-56

CAS No.: 1956370-21-0

RIPA-56 (RIPA56;RIPA 56)

货号: PC-42301Not For Human Use, Lab Use Only.

RIPA-56 is a highly potent, selective, stable Receptor-interacting protein 1 (RIPK1) inhibitor with IC50 of 13 nM.

规格 价格 库存 数量
25 mg ¥1880 In stock
50 mg ¥2980 In stock
100 mg ¥4880 In stock
200 mg Get quote
1 g Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

RIPA-56 is a highly potent, selective, stable Receptor-interacting protein 1 (RIPK1) inhibitor with IC50 of 13 nM.
RIPA-56 shows good selectivity in kinase panel screening, and does not IDO activity ( at >200 uM).
RIPA-56 efficiently protects mice from mTNFα-induced multi-organ damage.

物理化学性质&存储条件

分子量 221.29546
分子式 C13H19NO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Butanamide, N-hydroxy-2,2-dimethyl-N-(phenylmethyl)-

参考文献

1. Ren Y, et al. J Med Chem. 2017 Feb 9;60(3):972-986.

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