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首页-小分子抑制剂&激动剂-Apoptosis-RIP kinase-Citronellol
Citronellol

Chemical Structure : Citronellol

CAS No.: 106-22-9

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Citronellol ((±)-Citronellol)

货号: PC-23024Not For Human Use, Lab Use Only.

Citronellol is an orally active inducer of apoptosis and RIPK1 agonist.

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500 mg ￥280 In stock
1 g ￥480 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Citronellol is an orally active inducer of apoptosis and RIPK1 agonist.
Citronellol prevents oxidative stress, mitochondrial dysfunction, and apoptosis in the SH-SY5Y cell Parkinson's disease model induced by 6-OHDA by regulating the ROS-NO, MAPK/ERK, and PI3K/Akt signaling pathways.
Citronellol reduces the levels of LC-3 and p62 to regulate the autophagy pathway, inhibits oxidative stress and neuroinflammation, and thus have neuroprotective effects on Parkinson's rats.
Citronellol exhibits anti-fungal activity against Trichophyton rubrum by inhibiting ergosterol synthesis.

物理化学性质&存储条件

分子量 156.27
分子式 C10H20O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3,7-Dimethyloct-6-en-1-ol

参考文献

1. Gong Q, et al. Cell Commun Signal. 2024 Sep 2;22(1):427.

2. Munir S, et al. Biomedicines. 2023 Oct 18;11(10):2820.

3. Shao J, et al. Neurotox Res. 2022 Dec;40(6):2221-2237

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