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首页-小分子抑制剂&激动剂-Others-PCSK9

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Cat. No. Product Name Information
PC-70149

PF-06446846

PCSK9 inhibitor

PF-06446846 (PF-6446846) is a potent, highly selective inhibitor of PCSK9 translation with IC50 of 0.3 uM for inhibition the secretion of PCSK9 by Huh7 cells.
PC-22461

E28362

PCSK9 inhibitor

E28362 is a novel small-molecule PCSK9 inhibitor, effectively binds to PCSK9 (SPR KD=14.8 uM) and disrupts the PCSK9-LDLR interaction, promotes the degradation of PCSK9 via the ubiquitin-proteasome pathway.
PC-21266

NYX-1492

PCSK9 inhibitor

NYX-1492 is a small molecule PCSK9 inhibitor, blocks PCSK9 binding with the LDLR, attenuates inflammation in vascular cells and tissue-engineered blood vessels (TEBVs).

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