| Cat. No. |
Product Name |
Information |
| PC-60376 |
R-IMPP
PCSK9 secretion inhibitor
|
R-IMPP ((R)-IMPP, PF-00932239) is a small molecule inhibitor of PCSK9 secretion (IC50=4.8 uM) that selectively binds to human 80S ribosome, but not E. coli, ribosomes. |
| PC-70150 |
PF-06446846 hydrochloride
PCSK9 inhibitor
|
PF-06446846 hydrochloride (PF-6446846) is a potent, highly selective inhibitor of PCSK9 translation with IC50 of 0.3 uM for inhibition the secretion of PCSK9 by Huh7 cells. |
| PC-70149 |
PF-06446846
PCSK9 inhibitor
|
PF-06446846 (PF-6446846) is a potent, highly selective inhibitor of PCSK9 translation with IC50 of 0.3 uM for inhibition the secretion of PCSK9 by Huh7 cells. |
| PC-25615 |
PCSK9 inhibitor Pep2-8
PCSK9 inhibitor
|
Pep2-8 is a specific small peptide PCSK9 inhibitor with a binding KD of 0.7 μM, inhibits LDL receptor and EGF(A) domain binding to PCSK9 with IC50 values of 0.8 μMand 0.4 μM respectively, Pep2-8 is an EGF(A)-mimicking peptide and does not bind to other proprotein convertases. |
| PC-25140 |
Inclisiran
PCSK9 inhibitor
|
Inclisiran is a double-stranded small interfering RNA (siRNA) molecule that inhibit the transcription of PCSK9, inhibits Pyroptosis, activates PPARγ, and reduces NLRP3, cleaved caspase-1, IL-1β, and IL-18, shows anti-inflammatory, lipid-regulating and anti-atherosclerotic activities. |
| PC-24901 |
Pinostrobin
PCSK9 inhibitor
|
Pinostrobin is a flavonoid with anti-cancer, antioxidant, antiviral and neuroprotective activities, Pinostrobin is a potent PCSK9 inhibitor, inhibits PCSK9 promoter activity as well as the suppression of PCSK9 mRNA expression in HepG2 cells. |
| PC-24178 |
PCSK9 inhibitor 3f
PCSK9 inhibitor
|
PCSK9 inhibitor 3f is a small molecule, orally bioavailable inhibitor of PCSK9 that antagonizes PCSK9-LDLR interaction with IC50 of 537 nM. |
