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CVI-LM001

Chemical Structure : CVI-LM001

CAS No.:

CVI-LM001

货号: PC-26864Not For Human Use, Lab Use Only.

CVI-LM001 is a fluorobenzenesulfonate derivative of corydaline acting by suppressing the expression of PCSK9 gene and by stabilizing LDL mRNA, increases the LDL receptor levels by both inhibiting PCSK9 transcription and preventing LDL receptor mRNA degradation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CVI-LM001 is a fluorobenzenesulfonate derivative of corydaline acting by suppressing the expression of PCSK9 gene and by stabilizing LDL mRNA, increases the LDL receptor levels by both inhibiting PCSK9 transcription and preventing LDL receptor mRNA degradation.

物理化学性质&存储条件

分子量 450.55
分子式 C26H26O5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(6aS,12aS)-3,9-dimethoxy-5,6,6a,7,12,12a-hexahydrotetraphen-8-yl benzenesulfonate

参考文献

1. Ahamad S, et al. J Med Chem. 2022 Dec 8;65(23):15513-15539.

2. Ferri N, et al. Atheroscler Plus. 2024 Dec 12;59:25-31.

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