| Cat. No. |
Product Name |
Information |
| PC-60173 |
NK1-IN-9
NK1/SERT inhibitor
|
NK1-IN-9 is a potent, orally active, dual NK1 receptor antagonist (IC50=0.5 nM) and SERT inhibitor (IC50=5.2 nM). |
| PC-42191 |
Maropitant
NK1 receptor antagonist
|
Maropitant (CJ-11972) is a selective neurokinin 1 receptor (NK1) antagonist for prevention of vomiting due to motion sickness in dogs. |
| PC-42185 |
Aprepitant
NK-1 receptor inhibitor
|
Aprepitant (MK-0869) is a potent, orally active, long-acting human NK-1 receptor (substance P receptor) antagonist with IC50 of 0.09 nM. |
| PC-45396 |
NKP608
NK1 receptor antagonist
|
NKP608 (NKP-608) is a non-peptidic, specific, potent and orally active NK1 receptor antagonist with IC50 of 2.6 nM. |
| PC-44659 |
SB222200
NK3 receptor antagonist
|
SB-222200 (SB222200) is a CNS-penetrant, potent and selective NK-3 receptor antagonist with Ki of 4.4 nM (inhibition of neurokinin B binding to CHO-hNK-3R). |
| PC-23421 |
EB1002
NK2R agonist
|
EB1002 is a potent, selective, long-acting neurokinin 2 receptor (NK2R), enhances insulin sensitization. |
| PC-23398 |
Vofopitant dihydrochloride
NK1 receptor antagonist
|
Vofopitant dihydrochloride (GR 205171A) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist, inhibits [3H]SP binding to the NK1 receptor with pKi values of 9.5 and 10.6 in rat and human membranes respectively. |
| PC-23397 |
Vofopitant
NK1 receptor antagonist
|
Vofopitant (GR205171) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist, inhibits [3H]SP binding to the NK1 receptor with pKi values of 9.5 and 10.6 in rat and human membranes respectively. |
| PC-22655 |
SR140333B
NK1 receptor antagonist
|
Nolpitantium besilate (SR140333B) is a potent, selective, non-peptide NK1 receptor antagonist with Ki of 0.74 nM, IC50 of 1.6 nM. |
| PC-21757 |
Elinzanetant
NK1/3R inhibitor
|
Elizanetant (NT-814) is an orally active, selective neurokinin (NK) receptors 1 and 3 antagonist, modulates reproductive hormone secretion. |
