L-733060 hydrochloride | NK1 receptor antagonist | ProbeChem Biochemicals

Chemical Structure : L-733060 hydrochloride

加入收藏

L-733060 hydrochloride (L 733060 hydrochloride)

货号: PC-70194Not For Human Use, Lab Use Only.

L-733060 hydrochloride is an orally active, non-peptide, selective antagonist for the NK1 receptor with Ki of 0.8 nM.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

L-733060 hydrochloride is an orally active, non-peptide, selective antagonist for the NK1 receptor with Ki of 0.8 nM.
L-733060 hydrochloride inhibits neurogenic plasma extravasation in rat dura produced by electrical stimulation of trigeminal nerves with ID50 of 212 mg/kg, i.v.
L-733060 hydrochloride shows no effect on mean arterial blood pressure or heart rate in conscious or anaesthetised rats

物理化学性质&存储条件

分子量	439.82
分子式	C20H19F6NO · HCl
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,3S)-3-((3,5-bis(trifluoromethyl)benzyl)oxy)-2-phenylpiperidine hydrochloride

参考文献

1. Seabrook GR, et al. Eur J Pharmacol. 1996 Dec 12;317(1):129-35.

2. Rupniak NM, et al. Pain. 1996 Sep;67(1):189-95.

3. Rupniak NM, et al. Neuropharmacology. 2000 Jun 8;39(8):1413-21.

L-733060 hydrochloride (L 733060 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

L-733060 hydrochloride (L 733060 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.