NKP608 | NK1 receptor antagonist | Probechem Biochemicals

Chemical Structure : NKP608

CAS No.: 177707-12-9

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NKP608 (NKP-608)

货号: PC-45396Not For Human Use, Lab Use Only.

NKP608 (NKP-608) is a non-peptidic, specific, potent and orally active NK1 receptor antagonist with IC50 of 2.6 nM.

规格	价格	库存
5 mg	￥1980	In stock
10 mg	￥2980	In stock
25 mg	￥4880	In stock
50 mg	￥7880	In stock
100 mg		Get quote

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生物&药学活性

NKP608 (NKP-608) is a non-peptidic, specific, potent and orally active NK1 receptor antagonist with IC50 of 2.6 nM.
NKP608 exhibits an anxiolytic-like effect in the social interaction and social exploration test in rats; orally active.

物理化学性质&存储条件

分子量	619.9846
分子式	C31H24ClF6N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-Quinolinecarboxamide, N-[(2R,4S)-1-[3,5-bis(trifluoromethyl)benzoyl]-2-[(4-chlorophenyl)methyl]-4-piperidinyl]-

参考文献

1. Gentsch C, et al. Behav Brain Res. 2002 Jul 18;133(2):363-8.

2. Vassout A, et al. Regul Pept. 2000 Dec 22;96(1-2):7-16.

3. Coulson FR, et al. Inflamm Res. 2002 Jul;51(7):317-23.

NKP608 (NKP-608)

生物&药学活性

物理化学性质&存储条件

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NKP608 (NKP-608)

生物&药学活性

物理化学性质&存储条件

参考文献

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