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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Filovirus

Request The Product List ofFilovirus Filovirus

Cat. No. Product Name Information
PC-35009

JNJ-1A

DENV NS4B inhibitor

JNJ-1A is a novel Dengue virus (DENV) NS4B inhibitor that inhibits DENV-2 sub-genomic replicon at 0.7 μM, in the absence of cytotoxicity.
PC-35008

ST-148

DENV inhibitor

ST-148 is a potent, broad-spetrum inhibitor of dengue virus (DENV) replication, inhibits DENV-2 wth EC50 of 16 nM in viral titer reduction assays, interacts with the DENV capsid protein.
PC-35007

VGTI-A3-03

DENV inhibitor

VGTI-A3-03 is a potent, highly virus-specific inhibitor of DENV replication with greatest activity against DENV serotype 2 (IC50=25 nM), directly binds DENV capsid protein.
PC-63346

SFV785

NTRK1/MAPKAPK5 inhibitor

SFV785 (SRPIN-785) is a derivative of SRPIN340 that selectively inhibits NTRK1 and MAPKAPK5 kinase, shows anti-viral activity on HCV, DENV and yellow fever viruses.
PC-62053

FGI-106

EBOV inhibitor

FGI-106 is a broad-spectrum inhibitor of multiple blood-borne viruses (HCV, HBV, HIV) as well as emerging biothreats (Ebola, VEE, Cowpox, PRRSV infection) with EC50 of 0.2-10 uM.
PC-62052

FGI-104

Filovirus inhibitor

FGI-104 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67).
PC-62051

FGI-103

Filovirus inhibitor

FGI-103 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67).
PC-60960

MK-0608

HCV inhibitor

MK-0608 is a nucleoside analogue that shows potent inhibition for replication of several mosquito-borne flaviviruses including DENV and ZIKV.
PC-60313

GS-5734

SARS-CoV-2 inhibitor

GS-5734 (Remdesivir) is a monophosphoramidate prodrug of adenosine analogue that exhibits antiviral activity against multiple variants of EBOV (EC50=70-140 nM) and other filoviruses (EC50=0.019-1.48 uM) in cell-based assays.
PC-45503

Galidesivir

Viral RdRp inhibitor

Galidesivir (BCX4430) is a viral RNA-dependent RNA polymerase (RdRp) inhibitor that acts as a non-obligate RNA chain terminator, inhibits MERS-CoV, SARS-CoV and SARS-CoV-2.
PC-45502

Galidesivir hydrochloride

Viral RdRp inhibitor

Galidesivir hydrochloride (BCX4430) is a viral RNA-dependent RNA polymerase (RdRp) inhibitor that acts as a non-obligate RNA chain terminator, inhibits MERS-CoV, SARS-CoV and SARS-CoV-2.
PC-23620

Compound 3.47

EBOV inhibitor

Compound 3.47 is a small molecule antifilovirus compound, inhibits EboV infection by interfering with binding of cleaved virus glycoprotein (GP) to endosomal membrane protein Niemann-Pick C1 (NPC1).

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