JBJ-01-162-04 |CAS: 2313524-77-3 Probechem Biochemicals

Chemical Structure : JBJ-01-162-04

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JBJ-01-162-04

货号: PC-35947Not For Human Use, Lab Use Only.

JBJ-01-162-04 is a small molecule targeting the flavivirus E protein with broad-spectrum activity, shows activity against DENV in the infectivity assay with IC90 of 0.1 uM.

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生物&药学活性

JBJ-01-162-04 is a small molecule targeting the flavivirus E protein with broad-spectrum activity, shows activity against DENV in the infectivity assay with IC90 of 0.1 uM.
JBJ-01-162-04 binds to DENV2 E protein (sE2) with Kd of 1.4 uM, reduces DENV viral burden in vivo.

物理化学性质&存储条件

分子量	437.382
分子式	C22H14F3N5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-2-(benzofuran-2-yl)-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-2-oxoacetohydrazonoyl cyanide

参考文献

1. Li PC, et al. ACS Infect Dis. 2019 Jan 4. doi: 10.1021/acsinfecdis.8b00322.

JBJ-01-162-04

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物理化学性质&存储条件

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