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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Filovirus-FGI-106
FGI-106

Chemical Structure : FGI-106

CAS No.: 501081-38-5

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FGI-106 (FGI106)

货号: PC-62053Not For Human Use, Lab Use Only.

FGI-106 is a broad-spectrum inhibitor of multiple blood-borne viruses (HCV, HBV, HIV) as well as emerging biothreats (Ebola, VEE, Cowpox, PRRSV infection) with EC50 of 0.2-10 uM.

规格 价格 库存 数量
5 mg ￥1980 In stock
10 mg ￥3280 In stock
25 mg ￥5480 In stock
50 mg ￥5480 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

FGI-106 is a broad-spectrum inhibitor of multiple blood-borne viruses (HCV, HBV, HIV) as well as emerging biothreats (Ebola, VEE, Cowpox, PRRSV infection) with EC50 of 0.2-10 uM.
FGI-106 inhibits the interaction of TSG101 with its cognate viral ligands.
FGI-106 displays an ability to prevent lethality from Ebola in vivo; well-tolerated and orally bioavailable.

物理化学性质&存储条件

分子量 458.654
分子式 C28H38N6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Quino[8,7-h]quinoline-1,7-diamine, N,N'-bis[3-(dimethylamino)propyl]-3,8-dimethyl- (9CI)

参考文献

1. Kinch MS, et al. Am J Transl Res. 2009 Jan 5;1(1):87-98.

2. De Clercq E. Med Res Rev. 2013 Nov;33(6):1249-77.

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