FGI-104 | Filovirus inhibitor | Probechem Biochemicals

Chemical Structure : FGI-104

加入收藏

FGI-104 (FGI104)

货号: PC-62052Not For Human Use, Lab Use Only.

FGI-104 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67).

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

FGI-104 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67).
FGI-104 protects mice against a lethal challenge with a mouse-adapted strain of either ZEBOV or MARV-Ravn as a single intraperitoneal dose of 10 mg/kg.
FGI-104 reduces viremia and the viral burden in kidney, liver, and spleen tissues in a murine model of ZEBOV infection.

物理化学性质&存储条件

分子量	492.016
分子式	C28H30ClN3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)-6-[4-(hydroxymethyl)-3-methoxyphenyl]phenol

参考文献

1. Warren TK, et al. Antimicrob Agents Chemother. 2010 May;54(5):2152-9.

2. Haque A, et al. Antimicrob Agents Chemother. 2015 Oct;59(10):5892-902.

3. De Clercq E. Med Res Rev. 2013 Nov;33(6):1249-77.

FGI-104 (FGI104)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

FGI-104 (FGI104)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.