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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Filovirus

Request The Product List ofFilovirus Filovirus

Cat. No. Product Name Information
PC-23619

EBOV inhibitor Compound 7

EBOV inhibitor

EBOV inhibitor Compound 7 is a a small-molecule entry inhibitor of filoviruses, inhibits infectious EBOV and Marburg virus (MARV) in cell-based assays with IC50 of 10 μM and 12 μM, respectively.
PC-23617

CBS1129

Filovirus inhibitor

CBS1129 is a small molecule inhibitor of filovirus entry, shows potent inhibitory activity against entry of both Ebola and Marburg viruses in human cancer cell lines (EC50=2.4 uM, pseudovirus (HIV/EBOV) assay).
PC-23615

VUN65671

EBOV/MARV inhibitor

VUN65671 is a potent small molecule inhibitor of Ebola (EBOV) and Marburg (MARV) virus entry with EC50 of 0.31 uM and 0.82 uM.
PC-23175

Methylene Blue

DENV NS2B-NS3 inhibitor

Methylene blue (Basic Blue 9) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor, also is a Tau aggregation inhibitor, inhibits DENV NS2B-NS3 inhibitor (IC50=9 µM) and DENV infection in cells in the submicromolar range (EC50=0.36 µM).
PC-23174

Temoporfin

NS2B-NS3 inhibitor

Temoporfin (m-THPC) is a reduced porphyrin and potent second-generation photosensitizer, also is a potent flavivirus NS2B-NS3 interaction inhibitor with broad-spectrum antiviral activity.
PC-23173

NK-189

NS2B-NS3 inhibitor

NK-189 is a potent, specific flaviviral serine protease NS2B-NS3 inhibitor with submicromolar activities in viral replication assays (EC50=0.89 μM, DENV-2).
PC-23172

DENV NS2B-NS3 inhibitor 71

NS2B-NS3 inhibitor

DENV NS2B-NS3 inhibitor 71 is a potent, specific flaviviral serine protease NS2B-NS3 inhibitor with submicromolar activities in viral replication assays (EC50=0.24 μM, DENV-2).
PC-23171

NSC157058

NS2B-NS3 inhibitor

NSC157058 is a potent, allosteric inhibitor of ZIKV NS2B-NS3 protease with IC50 of 0.82 uM.
PC-23170

SYC-1307

NS2B-NS3 inhibitor

SYC-1307 is a potent, allosteric inhibitor of flavivirus NS2B-NS3 protease with IC50 of 0.2, 0.59, 0.59 and 0.78 uM for ZIKV, DENV2, DENV3 and WNV NS2B-NS3 respectively, shows submicromolar anti-orthoflaviviral efficacy in cells (EC50=0.3-0.6 uM).
PC-23167

EYU688 (NITD-688)

DENV NS4B inhibitor

EYU688 (NITD-688) is a potent, specific pan-serotype inhibitor of dengue virus (DENV) NS4B protein, shows EC50 of 8-38 nM against all four DENV serotypes.
PC-22506

CVM-2-12-2

DENV E protein inhibitor

CVM-2-12-2 is a selective and potent inhibitor of the envelope (E) protein of dengue virus (DENV), demonstrates potent antiviral activity.
PC-22064

ARDP0006

DENV inhibitor

ARDP0006 is a potent inhibitor of dengue virus (DENV) NS2B-NS3 protease with EC50 of 4.2 uM.

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