| Cat. No. |
Product Name |
Information |
| PC-62051 |
FGI-103
Filovirus inhibitor
|
FGI-103 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67). |
| PC-60960 |
MK-0608
HCV inhibitor
|
MK-0608 is a nucleoside analogue that shows potent inhibition for replication of several mosquito-borne flaviviruses including DENV and ZIKV. |
| PC-60313 |
Remdesivir
SARS-CoV-2 inhibitor
|
Remdesivir (GS-5734) is a monophosphoramidate prodrug of adenosine analogue that exhibits antiviral activity against multiple variants of EBOV (EC50=70-140 nM) and other filoviruses (EC50=0.019-1.48 uM) in cell-based assays. |
| PC-45503 |
Galidesivir
Viral RdRp inhibitor
|
Galidesivir (BCX4430) is a viral RNA-dependent RNA polymerase (RdRp) inhibitor that acts as a non-obligate RNA chain terminator, inhibits MERS-CoV, SARS-CoV and SARS-CoV-2. |
| PC-45502 |
Galidesivir hydrochloride
Viral RdRp inhibitor
|
Galidesivir hydrochloride (BCX4430) is a viral RNA-dependent RNA polymerase (RdRp) inhibitor that acts as a non-obligate RNA chain terminator, inhibits MERS-CoV, SARS-CoV and SARS-CoV-2. |
| PC-28691 |
PHA-690509
CDK inhibitor, ZIKV inhibitor
|
PHA-690509 is a cyclin-dependent kinase (CDK) inhibitor, inhibits Zika virus (ZIKV) infection with IC50 of 0.9 uM, inhibits ZIKV infection at a post-entry stage, suppresses infection-induced caspase-3 activity in different neural cells. |
| PC-28684 |
BNJ-495
|
BNJ-495 is potent, broad-spectrum inhibitor of dengue virus (DENV) nonstructural protein 4B (NS4B) with IC50 of 0.17 nM for DENV2. |
| PC-28410 |
MWAC-3634
EBOV glycoprotein inhibitor
|
MWAC-3634 is a potent small-molecule inhibitor targeting Ebola virus (EBOV) glycoprotein (GP), binds GP with high affinity (Kd=40.7 nM), potently neutralizes infection (IC50= 0.65 nM), inhibits EBOV entry through glycoprotein stabilization. |
| PC-26719 |
JNJ-1953
Orthoflavivirus NS2A inhibitor
|
JNJ-1953 is an orthoflavivirus inhibitor targeting multifunctional NS2A protein, shows nM potency against DENV-2 clinical isolates DENV-2/EDEN3295 and DENV-2/38865Y10, affects viral RNA synthesis and packaging. |
| PC-26381 |
Berbamine
EBOV inhibitor, Gal3 inhibitor
|
Berbamine is a natural bisbenzylisoquinoline alkaloidshows broad exhibits anti-tumor and anti-viral activies, inhibits Ebola virus (EBOV) and prevents SARS-CoV-2 entry. |
| PC-26380 |
Berbamine hydrochloride
EBOV inhibitor, Gal3 inhibitor
|
Berbamine hydrochloride is a natural bisbenzylisoquinoline alkaloidshows broad exhibits anti-tumor and anti-viral activies, inhibits Ebola virus (EBOV) and prevents SARS-CoV-2 entry. |
| PC-24464 |
HeE1-2Tyr
Flavivirus RdRp inhibitor
|
HeE1-2Tyr is a potent, nonnucleoside inhibitor of flavivirus RNA dependent RNA polymerase (RdRp) with IC50 of 1.5 uM and 3.4 uM for DENV3 and WNV RdRps, respectively, also is a SARS-CoV-2 RdRp with IC50 of 27.6 uM. |
