欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Filovirus-Berbamine
Berbamine

Chemical Structure : Berbamine

CAS No.: 478-61-5

加入收藏

Berbamine

货号: PC-26381Not For Human Use, Lab Use Only.

Berbamine is a natural bisbenzylisoquinoline alkaloidshows broad exhibits anti-tumor and anti-viral activies, inhibits Ebola virus (EBOV) and prevents SARS-CoV-2 entry.

规格 价格 库存 数量
5 mg ￥1280 In stock
10 mg ￥1980 In stock
25 mg ￥3480 In stock
50 mg Get quote
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Berbamine is a natural bisbenzylisoquinoline alkaloidshows broad exhibits anti-tumor and anti-viral activies, inhibits Ebola virus (EBOV) and prevents SARS-CoV-2 entry.
Berbamine is a potent, brain penetrant Galectin-3 (Gal3) inhibitor, disrupts Gal3 oligomerization and Gal3-TREM2 interaction.
Berbamine also inhibit Ebola virus (EBOV) by targeting viral glycoprotein, disrupts GPcl-NPC1 interaction.
Berbamine prevents SARS-CoV-2 entry and transmission.
Berbamine effectively improved motor functions, reduced mutant huntingtin protein aggregation, and restored crucial dopaminergic and ciliary signaling pathways in R6/2 mouse model of Huntington's disease (HD).
Berbamine promotes ferroptosis of esophageal squamous cell carcinoma by facilitating USP51-mediated GPX4 ubiquitination and degradation.

物理化学性质&存储条件

分子量 608.74
分子式 C37H40N2O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(11S,31R)-16,36,37-Trimethoxy-12,32-dimethyl-11,12,13,14,31,32,33,34-octahydro-2,6-dioxa-1(7,1),3(8,1)-diisoquinolina-5(1,3),7(1,4)-dibenzenacyclooctaphan-54-ol

参考文献

1. Siew JJ, et al. Brain. 2026 Mar 3:awag069.

2. Panapakam J, et al. Sci Rep. 2026 Feb 20. doi: 10.1038/s41598-026-40631-2.

3. Yi D, et al. Acta Pharm Sin B. 2022 Dec;12(12):4378-4389.

4. Sadhu S, et al. iScience. 2024 Nov 8;27(12):111347.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: