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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Filovirus-PHA-690509
PHA-690509

Chemical Structure : PHA-690509

CAS No.: 492445-28-0

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PHA-690509 (PHA690509)

货号: PC-28691Not For Human Use, Lab Use Only.

PHA-690509 is a cyclin-dependent kinase (CDK) inhibitor, inhibits Zika virus (ZIKV) infection with IC50 of 0.9 uM, inhibits ZIKV infection at a post-entry stage, suppresses infection-induced caspase-3 activity in different neural cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PHA-690509 is a cyclin-dependent kinase (CDK) inhibitor, inhibits Zika virus (ZIKV) infection with IC50 of 0.9 uM, inhibits ZIKV infection at a post-entry stage, suppresses infection-induced caspase-3 activity in different neural cells.

物理化学性质&存储条件

分子量 331.43
分子式 C17H21N3O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-2-(4-acetamidophenyl)-N-(5-isopropylthiazol-2-yl)propanamide

参考文献

1. Miao Xu, et al. Nat Med. 2016 Oct;22(10):1101-1107.

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