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首页-小分子抑制剂&激动剂-Apoptosis-Ferroptosis

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Cat. No. Product Name Information
PC-22423

Erastin

Ferroptosis inducer

Erastin is a specific ferroptosis-inducing compound, shows RAS-selective lethality, also targetsvoltage-dependent anion channel 3 (VDAC3).
PC-21713

GPX4 inhibitor A16

GPX4 inhibitor

GPX4 inhibitor A16 is a potent, selective and covalent inhibitor of glutathione peroxidase 4 (GPX4), shows potent anti-proliferation activity the pancreatic cancer cell line AsPC-1 with IC50 of 22 nM.
PC-20924

FerroLOXIN-2

Ferroptosis inhibitor

FerroLOXIN-2 is a specific, small-molecule inhibitor of ferroptosis, inhibits 15LOX/PEBP1 catalytic complex rather than 15LOX alone, effectively suppresses ferroptosis in vitro and in vivo.
PC-20923

FerroLOXIN-1

Ferroptosis inhibitor

FerroLOXIN-1 is a specific, small-molecule inhibitor of ferroptosis, inhibits 15LOX/PEBP1 catalytic complex rather than 15LOX alone, effectively suppresses ferroptosis in vitro and in vivo.
PC-20811

FSEN1

FSP1 inhibitor

FSEN1 (Ferroptosis Sensitizer 1) is a specific small molecule, uncompetitive inhibitor of ferroptosis suppressor protein 1 (FSP1) with IC50 of 133 nM, sensitizes cancer cells to ferroptosis.
PC-20810

AKI-02

Ferroptosis inhibitor

AKI-02 is a hydroxypyridinone-based iron chelator, potently inhibits labile iron-mediated ferroptosis.

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