Ferroptosis compound (inhibitors, antagonists, inducers)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-26934	GPX4 inhibitor C18 GPX4 inhibitor	GPX4 inhibitor C18 (GPX4-IN-5) is a covalent inhibitor of glutathione peroxidase 4 (GPX4), shows remarkable inhibitory activity against TNBC cells with IC50 of 10-75 nM.
PC-25538	Deferoxamine mesylate Iron chelator, Ferroptosis inhibitor	Deferoxamine mesylate (DFOM) is a small molecule iron chelator and ferroptosis inhibitor, upregulates HIF-1α levels with good antioxidant activity, also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells.
PC-25537	Deferoxamine Iron chelator, Ferroptosis inhibitor	Deferoxamine (DFO) is a small molecule iron chelator and ferroptosis inhibitor, upregulates HIF-1α levels with good antioxidant activity, also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells.
PC-24932	Acevaltrate Ferroptosis inducer	Acevaltrate is a novel ferroptosis inducer and dual inhibitor of PCBP1/2 and GPX4, also inhibits the Na+/K+-ATPase activity in the rat kidney and brain hemispheres with IC50s of 22.8 μM and 42.3 μM, respectively.
PC-23010	Salinomycin Ferroptosis inducer	Salinomycin is a polyether ionophore antibacterial agent that shows effects on mitochondrial ion translocation and respiration, inhibits Wnt/β-catenin signaling, blocks Wnt-induced LRP6 phosphorylation and induces ferroptosis in cancer cells.

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