| Cat. No. |
Product Name |
Information |
| PC-63537 |
Astex ERK inhibitor X
ERK1/2 inhibitor
|
Astex ERK inhibitor X (ERK inhibitor 29) is a potent, selective ERK1/2 inhibitor that inhibits ERK catalytic activity with IC50 of 3 nM. |
| PC-63271 |
AZD0364
ERK1/2 inhibitor
|
Tizaterkib (AZD0364) is a potent, selective, ATP competitive, orally active ERK1/2 inhibitor with IC50 of 0.66 nM in ERK2 biochemical assay, binds similarly to ERK1 and ERK2 with Ki of 3.9 and 3.8 nM. |
| PC-42937 |
FR 180204
ERK1/2 inhibitor
|
FR 180204 is a potent, selective, ATP-competitive ERK inhibitor with Ki of 0.31 and 0.14 uM for ERK1 and ERK2, respectively. |
| PC-62596 |
MK-8353 hydrochloride
|
MK-8353 hydrochloride (SCH-900353) is a highly potent, orally bioavailable, dual-specificity ERK1/2 inhibitor with IC50 of 23.0/8.8 nM, respectively. |
| PC-62595 |
MK-8353
ERK1/2 inhibitor
|
MK-8353 (SCH-900353) is a highly potent, orally bioavailable, dual-specificity ERK1/2 inhibitor with IC50 of 23.0/8.8 nM, respectively. |
| PC-61978 |
KO-947
ERK1/2 inhibitor
|
KO-947 (KO947) is a potent and selective inhibitor of ERK1/2 kinase in biochemical, cellular and in vivo antitumor activity assays. |
| PC-61973 |
LY3214996
ERK1/2 inhibitor
|
Temuterkib (LY-3214996) is a novel potent, selective, orally active ERK1/2 inhibitor with IC50 of 5 nM for both enzymes in biochemical assays. |
| PC-70300 |
AX-15836
ERK5 inhibitor
|
AX-15836 (AX15836) is a potent, highly selective ERK5 inhibitor with IC50 of 8 nM. |
| PC-42663 |
Pluripotin
ERK1 inhibitor
|
Pluripotin(SC1) is a small molecule that can maintain the self-renewal of mESC (murine embryonic stem cells) in the absence of feeder cells and exogenous factors. |
| PC-45562 |
DEL-22379
ERK dimerization inhibitor
|
DEL-22379 (DEL22379) is a small molecule inhibitor of ERK dimerization with IC50 of 0.5 uM, without affecting ERK phosphorylation. |
| PC-43855 |
VX-11e
ERK2 inhibitor
|
VX-11e is a potent, selective, and orally bioavailable inhibitor of ERK2 with Ki of <2 nM. |
| PC-45868 |
SCH772984
ERK1/2 inhibitor
|
SCH772984 is a potent and selective inhibitor of ERK1/ERK2 with IC50 of 4 nM/1 nM, respectively. |
