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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-ERK-DEL-22379
DEL-22379

Chemical Structure : DEL-22379

CAS No.: 181223-80-3

DEL-22379 (DEL22379, DEL 22379)

货号: PC-45562Not For Human Use, Lab Use Only.

DEL-22379 (DEL22379) is a small molecule inhibitor of ERK dimerization with IC50 of 0.5 uM, without affecting ERK phosphorylation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

DEL-22379 (DEL22379) is a small molecule inhibitor of ERK dimerization with IC50 of 0.5 uM, without affecting ERK phosphorylation.
DEL-22379 prevents tumorigenesis by RAS-ERK pathway oncogenes.

物理化学性质&存储条件

分子量 444.5255
分子式 C26H28N4O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 30 mg/mL

Chemical Name/SMILES

1-Piperidinepropanamide, N-[2,3-dihydro-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-1H-indol-5-yl]-

参考文献

1. Herrero A, et al. Cancer Cell. 2015 Aug 10;28(2):170-82.

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