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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-ERK

Request The Product List ofERK ERK

Cat. No. Product Name Information
PC-22946

EI-52

ERK-MYD88 inhibitor

EI-52 is a small molecule inhibitor of ERK-MYD88 interaction, binds ERK1/2 (Kd=4.3/2.1 uM), inhibits ERK1/2-MYD88 interaction with IC50 of 3.1/14.7 uM in HTRF assays, induces cancer cell death.
PC-22834

XMD8-92

ERK5 inhibitor

XMD8-92 a specific small-molecule inhibitor of Big mitogen-activated protein kinase 1 (BMK1, ERK5) with Kd of 80 nM, IC50 of 1.5 uM in cell-free assays.
PC-22330

Ravoxertinib

ERK inhibitor

Ravoxertinib (GDC-0994) is potent, selective and orally active ERK kinase inhibitor with IC50 of 6.1 nM and 3.1 nM for ERK1 and ERK2, respectively.

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