ERK (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-24130	SKLB-D18 ERK1/2/5 inhibitor	SKLB-D18 is a potent, selective, first-in-class inhibitor of extracellular-regulated kinase 1/2 (ERK1/2) ERK1/2 and ERK5 with IC50 of 38.69/ 40.12 / 59.72 nM respecitvely.
PC-22946	EI-52 ERK-MYD88 inhibitor	EI-52 is a small molecule inhibitor of ERK-MYD88 interaction, binds ERK1/2 (Kd=4.3/2.1 uM), inhibits ERK1/2-MYD88 interaction with IC50 of 3.1/14.7 uM in HTRF assays, induces cancer cell death.
PC-22834	XMD8-92 ERK5 inhibitor	XMD8-92 a specific small-molecule inhibitor of Big mitogen-activated protein kinase 1 (BMK1, ERK5) with Kd of 80 nM, IC50 of 1.5 uM in cell-free assays.
PC-22330	Ravoxertinib ERK inhibitor	Ravoxertinib (GDC-0994) is potent, selective and orally active ERK kinase inhibitor with IC50 of 6.1 nM and 3.1 nM for ERK1 and ERK2, respectively.

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