Chemical Structure : Magnolin
CAS No.: 31008-18-1
货号: PC-28581Not For Human Use, Lab Use Only.
Magnolin is a major component of Magnolia liliiflora, inhibits the Ras/ERKs/RSK2 signaling axis by targeting the active pocket of ERK1 and ERK2 with IC50 of 87 nM and 16.5 nM, respectively, has excellent antioxidant, anti-inflammatory and anti-cancer properties, also is a selective HCAR1 inhibitor with IC50 of 7.1 uM.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 mg | ¥780 | In stock | |
| 50 mg | ¥1180 | In stock | |
| 100 mg | ¥1880 | In stock | |
| 250 mg | Get quote | ||
| 1 g | Get quote |
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Magnolin is a major component of Magnolia liliiflora, inhibits the Ras/ERKs/RSK2 signaling axis by targeting the active pocket of ERK1 and ERK2 with IC50 of 87 nM and 16.5 nM, respectively, has excellent antioxidant, anti-inflammatory and anti-cancer properties, also is a selective HCAR1 inhibitor with IC50 of 7.1 uM.
| 分子量 | 416.47 | |
| 分子式 | C23H28O7 | |
| 外观性状 | Solid | |
| 储存条件 |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(1S,3aR,4S,6aR)-1-(3,4-Dimethoxyphenyl)-4-(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan |
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1. Lee CJ, et al. BMC Cancer. 2015 Aug 8;15:576.
2. Zheng L, et al. Chem Commun (Camb). 2026 Oct 14. doi: 10.1039/d6cc02998a.
3. Zhang M, et al. Int Immunopharmacol. 2024 Jun 15;134:112181.
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