| Cat. No. |
Product Name |
Information |
| PC-45958 |
Abiraterone acetate
CYP17A1 inhibitor
|
Abiraterone acetate (CB-7598) is a potent and irreversible CYP17A1 inhibitor with IC50 of 4 nM for 17α-hydroxylase. |
| PC-45936 |
Galeterone
CYP17A1 inhibitor
|
Galeterone (TOK-001, VN-124-1) is a potent 17α-hydroxylase/17,20-lyase (CYP17A1) inhibitor with IC50 of 300 nM. |
| PC-42617 |
Cobicistat
CYP3A inhibitor
|
Cobicistat (GS-9350) is a pharmacoenhancer that acts as potent and selective inhibitor of human CYP3A with IC50 of 30-285 nM. |
| PC-45969 |
Bergaptol
CYP3A4 inhibitor
|
Bergaptol is a natural furanocoumarin that is found to be a potent inhibitor of debenzylation activity of CYP3A4 enzyme with IC50 of 24.92 uM. |
| PC-42626 |
Orteronel
CYP17A1 inhibitor
|
Orteronel (TAK-700) is a highly selective CYP17A1 (17,20-lyase) inhibitor with IC50 of 17 nM for human 17,20-lyase. |
| PC-26843 |
CYP4Z1-IN-1
CYP4Z1 inhibitor
|
CYP4Z1-IN-1 (Compound 7c) is a potent, selective CYP4Z1 inhibitor with IC50 of 41.8 nM, >30-fold selective over CYP4F12, decreases the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in breast cancer cells. |
| PC-25318 |
CYP1B1 inhibitor B20
CYP1B1 inhibitor
|
CYP1B1 inhibitor B20 is a potent, highly selective CYP1B1 inhibitor with IC50 of 1.48 nM, does not inhibit CYP1A1 and CYP1A2 (IC50>80 uM). |
| PC-25295 |
CYP1A1 inhibitor 38
CYP1A1 inhibitor
|
CYP1A1 inhibitor 38 is a small molecule cytochrome P4501A1 (CYP1A1) inhibitor with IC50 of 0.02 uM and 0.001 uM in Caco-2 and CYhiRAW cells respectively, promotes macrophage phagocytosis, enhances macrophage-mediated bacterial clearance in vivo by inhibiting CYP1A1. |
| PC-25294 |
CYP1A1 inhibitor 47
CYP1A1 inhibitor
|
CYP1A1 inhibitor 47 is a small molecule cytochrome P4501A1 (CYP1A1) inhibitor with IC50 of 0.2 uM and 0.01 uM in Caco-2 and CYhiRAW cells respectively, promotes macrophage phagocytosis, enhances macrophage-mediated bacterial clearance in vivo by inhibiting CYP1A1. |
| PC-24523 |
17-ODYA
CYP450 inhibitor
|
17-ODYA (17-octadecynoic acid) is a CYP450 omega-hydroxylase ( CYP450 ω) inhibitor CYP450 ω-hydroxylase inhibitor, also inhibits the formation of 20-hydroxyeicosatetraenoic acid (20-HETE), epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids by rat renal cortical microsomes incubated with arachidonic acid. |
| PC-24397 |
SCM-08
CYP3A4 inhibitor
|
SCM-08 is a potent, selective, non-suicide CYP3A4 inhibitor with IC50 of 0.43 uM in P450-Glo inhibition assays, 47-fold selecitve over CYP3A5. |
| PC-24396 |
SCM-18
CYP3A4 inhibitor
|
SCM-18 is a potent, highly selective, non-suicide CYP3A4 inhibitor with IC50 of 0.36 uM, has >170 fold selectivity over CYP3A5 (IC50>60 uM). |
