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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Cytochrome P450 (CYPs)-Methoxsalen
Methoxsalen

Chemical Structure : Methoxsalen

CAS No.: 298-81-7

Methoxsalen (8-Methoxypsoralen, Xanthotoxin, 8-MOP)

货号: PC-45788Not For Human Use, Lab Use Only.

Methoxsalen (8-Methoxypsoralen, Xanthotoxin, 8-MOP) is a potent tricyclic furocoumarin suicide that used to treat psoriasis, eczema, vitiligo and some cutaneous lymphomas in conjunction with exposing the skin to sunlight.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Methoxsalen (8-Methoxypsoralen, Xanthotoxin, 8-MOP) is a potent tricyclic furocoumarin suicide that used to treat psoriasis, eczema, vitiligo and some cutaneous lymphomas in conjunction with exposing the skin to sunlight.
Methoxsalen inhibits human CYP2A6 and mouse CYP2A5, inhibits nicotine metabolism and alters the behavioral effects of nicotine in the mouse.
Methoxsalen also induces Ca2+ entry in MG63 human osteosarcoma cells.

物理化学性质&存储条件

分子量 216.1895
分子式 C12H8O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

7H-Furo[3,2-g][1]benzopyran-7-one, 9-methoxy-

参考文献

1. Lu YC, et al. Chin J Physiol. 2017 Jun 30;60(3):174-182.

2. Alsharari SD, et al. Nicotine Tob Res. 2014 Jan;16(1):18-25.

3. Bagdas D, et al. Neuropharmacology. 2014 Oct;85:67-72.

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