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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Cdc2-like Kinase (CLK)

Request The Product List ofCdc2-like Kinase (CLK) Cdc2-like Kinase (CLK)

Cat. No. Product Name Information
PC-22056

CLK2 inhibitor LQ23

CLK2 inhibitor

CLK2 inhibitor LQ23 is a potent, selective cdc2-like kinase 2 (CLK2) inhibitor with IC50 of 1.4 nM, >70-fold selecitve over CLK3.
PC-21435

SM04755

CLK inhibitor

Teplinovivint (SM04755) is a small molecule canonical Wnt signaling inhibitor, potently inhibited CLK2, CLK3, and DYRK1A with IC50 of 5.0 nM, 48.6  nM and 3.5 nM, respectively.
PC-20895

MW01

CLK inhibitor

MW01 is a specific inhibitor for DNA damage-induced NF-κB activity, inhibits CLK2 and CLK4 with IC50 of 360 and 14.1 nM, does not inhibit CLK3.
PC-20894

MW05

CLK inhibitor

MW05 is a specific inhibitor for DNA damage-induced NF-κB activity, inhibits CLK2 and CLK4 with IC50 of 1400 and 307 nM, does not inhibit CLK3.
PC-20474

GPS192

CLK inhibitor

GPS192 (GPS 167) is a specific small molecule splicing regulator SRSF10 inhibitor, modulates BCLAF1 splicing with IC50 of 2 uM in human colorectal HCT116 cells, directly inhibits CLK1, CLK2 and CLK4, but not SRPK1 and DYRK1A.
PC-73374

CLK4 inhibitor 96

CLK4 inhibitor

CLK4 inhibitor 96 is a novel potent CLK4 inhibitor with IC50 of 57.5 nM.
PC-73373

GPS167

CLK inhibitor, SRSF10 inhibitor

GPS167 is a specific small molecule splicing regulator SRSF10 inhibitor, modulates BCLAF1 splicing with IC50 of 2 uM in human colorectal HCT116 cells, directly inhibits CLK1, CLK2 and CLK4, but not SRPK1 and DYRK1A.
PC-72906

Ipivivint

CLK inhibitor

Ipivivint is a potent, selective CLK inhibitor, inhibits Wnt pathway signaling gene expression through inhibiting CLK activity and serine and SRSF phosphorylation.
PC-72778

TG003

CLK inhibitor

TG003 (TG-003) is a potent, specific, reversible, and ATP-competitive inhibitor of Cdc2-like kinase (CLK) with IC50 of 20, 200 and 15 nM for mClk1, 2 and 4 respectively, and >10 uM for mClk3
PC-72099

Cirtuvivint

CLK inhibitor

Cirtuvivint (SM08502) is a novel potent, selective inhibitor of CDC-like kinase (CLK) with IC50 of 2/22 nM against CLK2/3.
PC-35987

MU1210

CLK inhibitor

MU1210 (MU-1210) is a potent and highly selective inhibitor of cdc-like kinases (CLKs) with IC50 of 51 nM (cellular BRET for CLK1).
PC-35359

CLK2 inhibitor Indazole 1

CLK2 inhibitor

CLK2 inhibitor Indazole1 is a novel potent, selective inhibitor of CLK2 with IC50 of 2.7 nM, 60-fold selectivity over PKA and >600-fold selectivity over a panel of 34 kinases.

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