Caspase compound (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-24053	ORF9b homodimerization inhibitor EN300 ORF9b inhibitor	ORF9b homodimerization inhibitor EN300 is a small molecule inhibitor of ORF9b homodimerization, inhibits ORF9b-ORF9b homotypic interaction, inhibits activation of caspase-1 in A549.ORF9b and THP-1.ORF9b cells with IC50 of 0.85 and 17 nM respectively.
PC-23805	FLIPinBγ c-FLIPL inhibitor	FLIPinBγ is a first-in class, specific small molecule inhibitor of c-FLIPL in the caspase-8/c-FLIPL heterodimer, promotes CD95L- and TRAIL-mediated loss of cell viability and cell death.
PC-22972	Pralnacasan Caspase-1 inhibitor	Pralnacasan (VX-740) is a potent, selective, non-peptide and orally active caspase 1 (interleukin-1β converting enzyme, ICE) inhibitor with Ki of 1.4 nM, inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ.
PC-22751	Z-YVAD-FMK Caspase-1 inhibitor	Z-YVAD-FMK is a specific, cell-permeable and irreversible caspase-1 inhibitor with anti-inflammatory and anti-tumor activities.
PC-22034	CZL80 Caspase-1 inhibitor	Caspase-1 inhibitor CZL80 is a potent, selective, brain‐penetrable Caspase-1 inhibitor with IC50 of 0.01 uM.

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