Emricasan (IDN-6556, PF-03491390)

Chemical Structure : Emricasan

CAS No.: 254750-02-2

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货号: PC-62433Not For Human Use, Lab Use Only.

Emricasan (IDN-6556, PF-03491390) is a potent, irreversible pan-caspase inhibitor, shows neuroprotective activity for hNPCs, inhibits ZIKV-induced increased caspase-3 activity.

规格	价格	库存
5 mg	￥980	In stock
10 mg	￥1480	In stock
50 mg	￥3580	In stock
100 mg		Get quote

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生物&药学活性

Emricasan (IDN-6556, PF-03491390) is a potent, irreversible pan-caspase inhibitor, shows neuroprotective activity for hNPCs, inhibits ZIKV-induced increased caspase-3 activity.

物理化学性质&存储条件

分子量	569.51
分子式	C26H27F4N3O7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(3S)-3-[[(2S)-2-[[2-(2-tert-butylanilino)-2-oxoacetyl]amino]propanoyl]amino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid

参考文献

1. Xu M, et al. Nat Med. 2016 Oct;22(10):1101-1107.

2. Brumatti G, et al. Sci Transl Med. 2016 May 18;8(339):339ra69.

3. McCall MD, et al. Transplantation. 2012 Jul 15;94(1):30-5.