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首页-小分子抑制剂&激动剂-Apoptosis-Caspase-KEA1-97
KEA1-97

Chemical Structure : KEA1-97

CAS No.: 2138882-71-8

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KEA1-97 (KEA 1-97)

货号: PC-60171Not For Human Use, Lab Use Only.

KEA1-97 (KEA 1-97) is a small molecule that disrupts the interaction of thioredoxin with caspase 3.

规格 价格 库存 数量
10 mg ￥780 In stock
25 mg ￥1280 In stock
50 mg ￥2180 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

KEA1-97 (KEA 1-97) is a small molecule that disrupts the interaction of thioredoxin with caspase 3.
KEA1-97 activates caspases, and induces apoptosis without affecting thioredoxin activity, impairs triple-negative breast cancer cell survival.
KEA1-97 impairs in vivo breast tumor xenograft growth.

物理化学性质&存储条件

分子量 335.163
分子式 C15H9Cl2FN4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: 100 mg/mL
Chemical Name/SMILES

4,6-dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine

参考文献

1. Anderson KE, et al. ACS Chem Biol. 2017 Oct 20;12(10):2522-2528.

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