| Cat. No. |
Product Name |
Information |
| PC-60599 |
ROC-325
Autophagy inhibitor
|
ROC-325 (ROC 325, ROC325) is a novel, orally available inhibitor of lysosomal-mediated autophagy. |
| PC-60217 |
AUTEN-67
MTMR14 inhibitor, autophagy inducer
|
AUTEN-67 is a small molecule autophagy enhancer that specificly inhibits myotubularin-related phosphatase MTMR14. |
| PC-70067 |
AUTEN-99
MTMR14 inhibitor, autophagy inducer
|
AUTEN-99 is a small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy. |
| PC-70066 |
AUTEN-99 hydrobromide
MTMR14 inhibitor, autophagy inducer
|
A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy. |
| PC-45633 |
Hemin
CLEC-2 agonist, HO-1 inducer
|
Hemin is an iron-containing porphyrin as heme oxygenase (HO)-1 inducer, also is a CLEC-2 agonist that induces CLEC-2-mediated platelet aggregation. |
| PC-42080 |
SMER28
VCP/p97 activator
|
SMER28 is a small-molecule enhancer/inducer of Autophagy, SMER28 is a small molecule activator of VCP/p97. |
| PC-42248 |
STF-62247
Autophagy inducer
|
STF-62247 is a small molecule Autophagy inducer that induces autophagy and selectively induces lethality in VHL-deficient RCC cells. |
| PC-45515 |
SMER-18
Autophagy inducer
|
SMER-18 is a small molecule autophagy enhancer that induces autophagy independently of rapamycin in mammalian cells and enhances the clearance of autophagy substrates such as mutant huntingtin and A53T alpha-synuclein. |
| PC-24817 |
CIM7
CMA inhibitor, NCoR1/RARα inhibitor
|
CMA Inhibitory Molecule 7 (CIM7) is a potent and selective chaperone-mediated autophagy (CMA) inhibitor with IC50 of 75 nM (A549 cells, 24h), functions by disrupting the NCoR1/RARα interaction and altering the CMA regulatory transcriptional program to suppress CMA. |
| PC-24786 |
Chloroquine
Autophagy inhibitor
|
Chloroquine is an antimalarial drug and autophagy/lysosome inhibitor, inhibiting Toll-like receptor (TLR) signalling. |
| PC-24731 |
Autogramin-2
GRAMD1A inhibitor, Autophagy inhibitor
|
Autogramin-2 is a small molecule autophagy inhibitor with IC50 of 0.27 uM (amino acid starvation), specifically binds to the StART domain of GRAM domain containing 1A (GRAMD1A, Aster-A) and also specifically inhibits the cholesterol-transfer activity of GRAMD1A. |
| PC-24604 |
TH152
LC3/GABARAP ligand
|
TH152 is a potent reversible pan-LC3/GABARAP ligand with KD of 2 µM for LC3A in ITC assays, binds all Atg8 family proteins with comparable affinity. |
