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首页-小分子抑制剂&激动剂-Autophagy-Lys01
Lys01

Chemical Structure : Lys01

CAS No.: 1391426-22-4

Lys01 (Lys 01, Lys-01)

货号: PC-60600Not For Human Use, Lab Use Only.

Lys01 is a 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ), inhibits cell viability of 1205Lu, c8161, LN229, HT-29 cells with IC50s of 3.6, 3.8, 7.9, 6.0 uM respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Lys01 is a 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ), inhibits cell viability of 1205Lu, c8161, LN229, HT-29 cells with IC50s of 3.6, 3.8, 7.9, 6.0 uM respectively.

物理化学性质&存储条件

分子量 440.372
分子式 C23H23Cl2N5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N2-(7-Chloro-4-quinolinyl)-N1-[2-[(7-chloro-4-quinolinyl)amino]ethyl]-N1-methyl-1,2-ethanediamine

参考文献

1. McAfee Q, et al. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8253-8.

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