| Cat. No. |
Product Name |
Information |
| PC-38198 |
TAS0612
YBX1 inhibitor
|
TAS0612 (TAS-0612) is an orally bioavailable multikinase inhibitor of AKT, p70S6K, and p90RSK, inhibits Y-box-binding protein (YBX1) phosphorylation. |
| PC-36126 |
Borussertib
Akt inhibitor
|
Borussertib is a potent, first-in-class, covalent-allosteric AKT inhibitor with IC50 of 0.8 nM and Ki of 2.2 nM for WT Akt. |
| PC-35326 |
Ch-319
Akt inhibitor
|
Ch-319 (Ch319) is a triphenyltin (IV) carboxylate derivative that modulates AKT/FOXO3a signaling and inhibits progression of prostate cancer. |
| PC-63553 |
TAS-117 hydrochloride
Akt inhibitor
|
TAS-117 (Pifusertib) hydrochloride is a highly selective, oral, allosteric pan-AKT inhibitor with IC50 of 4.8/1.6/44 nM for Akt1/Akt2/Akt3 respectively. |
| PC-43440 |
CCT128930
Akt inhibitor
|
CCT128930 is a potent, selective, ATP-competitive AKT inhibitor with IC50 of 6 nM (AKT2), 28-fold selectivity over the closely related PKA. |
| PC-43434 |
A-674563 hydrochloride
Akt inhibitor
|
A-674563 hydrochloride is a potent, selective and orally available AKT inhibitor with Ki of 11 nM (Akt1). |
| PC-43433 |
A-674563
Akt inhibitor
|
A-674563 is a potent, selective and orally available AKT inhibitor with Ki of 11 nM (Akt1). |
| PC-43370 |
Isobavachalcone
Akt inhibitor
|
Isobavachalcone (Corylifolinin, Isobacachalcone) is a chalcone constituent of Angelica keiskei that can induce apoptosis in several cancer cells, is a potent inhibitor of Akt signaling pathway. |
| PC-42878 |
PHT-427
Akt inhibitor
|
PHT-427 (PHT427) is a small-molecule Akt inhibitor that binds selectively to the PH domain of AKT with Ki of 2.4 uM, inhibits phospho-Ser473-AKT in Panc-1 cells with IC50 of 6.3 uM. |
| PC-42874 |
AT7867 dihydrochloride
p70S6K/Akt inhibitor
|
AT7867 dihydrochloride is a potent, ATP-competitive, orally available dual Akt and p70S6K inhibitor with Ki of 17-85 nM, also inhibits PKA with Ki of 20 nM. |
| PC-42873 |
AT7867
p70S6K/Akt inhibitor
|
AT7867 (AT-7867) is a potent, ATP-competitive, orally available dual Akt and p70S6K inhibitor with Ki of 17-85 nM, also inhibits PKA with Ki of 20 nM. |
| PC-62833 |
TAS-117
Akt inhibitor
|
TAS-117 is a highly selective, non-ATP competitive pan-Akt inhibitor with IC50 of 4.8/1.6/44 nM for Akt1/Akt2/Akt3 respectively. |
