| Cat. No. |
Product Name |
Information |
| PC-45876 |
Akt1/2-IN-17
Akt1/2 inhibitor
|
Akt1/2-IN-17 is a potent, selective dual Akt1 and Akt2 inhibitor with IC50 of 3.5 nM and 42 nM, respectively. |
| PC-42551 |
MK-2206 dihydrochloride
Akt inhibitor
|
MK-2206 dihydrochloride is a potent, orally active allosteric Akt inhibitor with IC50 of 5/12 nM for Akt1/Akt2 respectively. |
| PC-42484 |
GSK-690693
Akt inhibitor
|
GSK-690693 (GSK690693) is a potent, ATP competitive, pan-AKT inhibitor with IC50 of 2, 13, and 9 nM against AKT1, 2, and 3, respectively. |
| PC-42579 |
Rizavasertib
Akt inhibitor
|
Rizavasertib (A-443654) is a potent and selective Akt inhibitor with Ki of 0.16 nM for Akt1/2/3. |
| PC-42032 |
BAY-1125976
Akt inhibitor
|
BAY-1125976 is a potent and highly selective, allosteric AKT1/2 inhibitor with IC50 of 5.2/18 nM at 10 uM ATP. |
| PC-45903 |
Perifosine
Akt inhibitor
|
Perifosine (KRX-0401, D21266) is an oral bioavailable alkylphospholipid, acts as an Akt inhibitor and a PI3K inhibitor, induces p21(WAF1) expression in squamous carcinoma cells through a p53-independent pathway. |
| PC-42697 |
PF-AKT400
Akt inhibitor
|
PF-AKT400 is a broadly selective, potent, ATP-competitive Akt kinase inhibitor with IC50 of 0.5 nM (biochemical assay), and 0.31 nM (cell function assay). |
| PC-28694 |
Kaempferol 3-O-β-D-glucuronide
AKT/GSK3β activator
|
Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-glucuronide, RT1) is a metabolite of kaempferol that can be taken orally and has anti-inflammatory properties, activates AKT/GSK3β phosphorylation and improves glucose metabolism. |
| PC-27249 |
(E)-Akt inhibitor-IV
Akt inhibitor
|
(E)-Akt inhibitor-IV ((E)-AKTIV) is a small molecule Akt inhibitor, inhibits human breast cancer cell lines and one non-cancer breast cell line with GI20 of 0.04 uM. |
| PC-26392 |
Withanolide B
AKT modulator
|
Withanolide B is an active component of W. somnifera Dunal, effectively promotes human bone mesenchymal stem cells (hBMSCs) osteogenic differentiation via ERK1/2 and Wnt/β-catenin signaling pathways, is also a potent AKT modulator. |
| PC-26053 |
MK-2206
Akt inhibitor
|
MK-2206 is a potent, orally active allosteric Akt inhibitor with IC50 of 5/12 nM for Akt1/Akt2 respectively. |
| PC-25698 |
CTx-0294885
Broad kinase inhibitor
|
CTx-0294885 is a broad spectrum kinase inhibitor that can capture 235 kinases from MDA-MB-231 cells, and can capture all members of the AKT family. |
