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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-Akt

Request The Product List ofAkt Akt

Cat. No. Product Name Information
PC-42579

A-443654

Akt inhibitor

Rizavasertib (A-443654) is a potent and selective Akt inhibitor with Ki of 0.16 nM for Akt1/2/3.
PC-42032

BAY-1125976

Akt inhibitor

BAY-1125976 is a potent and highly selective, allosteric AKT1/2 inhibitor with IC50 of 5.2/18 nM at 10 uM ATP.
PC-45903

Perifosine

Akt inhibitor

Perifosine (KRX-0401, D21266) is an oral bioavailable alkylphospholipid, acts as an Akt inhibitor and a PI3K inhibitor, induces p21(WAF1) expression in squamous carcinoma cells through a p53-independent pathway.
PC-42697

PF-AKT400

Akt inhibitor

PF-AKT400 is a broadly selective, potent, ATP-competitive Akt kinase inhibitor with IC50 of 0.5 nM (biochemical assay), and 0.31 nM (cell function assay).
PC-24887

ML-B01

Akt inhibitor

ML-B01 is an ipatasertib analog and selective Akt inhibitor with IC50 of 2.0 nM and 136 nM for Akt1 and PKA respectively.
PC-23340

Triciribine

Akt inhibitor

Triciribine is a purine analog and DNA synthesis inhibitor, also inhibits Akt and HIV-1/2 with IC50 of 130 nM, and 0.02-0.46 μM, respectively, selectively inhibits the phosphorylation and activation of all three Akt isoforms.

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