| Cat. No. |
Product Name |
Information |
| PC-20987 |
Difluorophenyl Quinazoline
β2AR NAM
|
Difluorophenyl Quinazoline (DFPQ, AP-06-202) is a selective, biased, negative allosteric modulator (NAM) of β-arrestin recruitment to β2-adrenergic receptor (β2AR), without effect on on β2AR coupling to Gs. |
| PC-20804 |
Nebivolol hydrochloride
Beta adrenergic antagonist
|
Nebivolol hydrochloride (R 065824) is a beta adrenergic antagonist and shows direct vasodilator properties and adrenergic blocking characteristics. |
| PC-20307 |
BAY-6096
Adrenergic α2B inhibitor
|
BAY-6096 (BAY6096) is a potent, selective, and highly water-soluble adrenergic α2B antagonist with IC50 of 14 nM. |
| PC-49058 |
AS408
β2AR NAM
|
AS408 (AS-408) is a negative allosteric modulator (NAM) of the β2-adrenergic receptor (β2AR) for both G-protein activation and arrestin recruitment (pKB=6.8, [35S]GTPγS binding assays). |
| PC-47093 |
Tasipimidine
α2A adrenoceptor agonist
|
Tasipimidine is a potent, selective and orally active human α2A-adrenoceptor agonist with pEC50 of 7.57, >100-fold selectivity over α2B-and α2C-adrenoceptors and the rodent α2D-adrenoceptor. |
| PC-36084 |
Olodaterol hydrochloride
|
Olodaterol hydrochloride (BI1744 CL) is a potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2. |
| PC-35360 |
AGN192836
α2AR agonist
|
AGN192836 (AGN 192836) is a potent, selective α2 adrenergic (alpha 2-adrenoceptor, α2AR) agonist with EC50 of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively. |
| PC-35028 |
BI-167107
β2AR agonist
|
BI-167107 (BI 167107) is a highly potent agonist of the β2 adrenergic receptor (β2AR) and β1AR (IC50=3.2 nM) and shows some activity as α1A antagonist (IC50 = 32 nM). |
| PC-43176 |
Midodrine
α1-adrenoceptor agonist
|
Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension. |
| PC-43161 |
Yohimbine
α2 adrenoceptor antagonist
|
Yohimbine is an indole alkaloid that has high affinity for the α2-adrenergic receptors with Ki of 1 nM for α2A, α2B and α2C. |
| PC-43012 |
Atipamezole
α2 adrenoceptor agonist
|
Antipamezole (MPV-1248) is a potent, specific α2-adrenoceptor antagonist with Ki of 1.6 nM. |
| PC-43011 |
Atipamezole hydrochloride
α2-adrenoceptor antagonist
|
Antipamezole (MPV-1248) is a potent, specific α2-adrenoceptor antagonist with Ki of 1.6 nM. |
