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首页-小分子抑制剂&激动剂-GPCR-Adrenergic Receptor-Olodaterol hydrochloride
Olodaterol hydrochloride

Chemical Structure : Olodaterol hydrochloride

CAS No.: 869477-96-3

Olodaterol hydrochloride (BI1744 CL)

货号: PC-36084Not For Human Use, Lab Use Only.

Olodaterol hydrochloride (BI1744 CL) is a potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2.

规格 价格 库存 数量
5 mg ¥1980 In stock
10 mg ¥2880 In stock
25 mg ¥5580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Olodaterol hydrochloride (BI1744 CL) is a potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2; shows >250 fold selectivity over hβ1; exerts a bronchodilatory efficacy over 24 h in dogs and guinea pigs in the absence of systemic pharmacodynamic effects.

COPD

Phase 3 Clinical

物理化学性质&存储条件

分子量 413.895
分子式 C21H17ClFN3OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(4-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-5-yl)pyridine hydrochloride

参考文献

1. Bouyssou T, et al. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1410-4.

2. Bouyssou T, et al. J Pharmacol Exp Ther. 2010 Jul;334(1):53-62.

3. Wex E, et al. Br J Pharmacol. 2015 Jul;172(14):3537-47.

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