| Cat. No. |
Product Name |
Information |
| PC-22867 |
AGN-762
α2B/α2C adrenergic receptor activator
|
AGN-762 is a selective activator of α2B- and α2C-adrenergic receptor subtypes, but not the α2A subtype. |
| PC-22600 |
WB4101
α1A adrenoceptor antagonist
|
WB4101 is a potent, α1A-adrenergic selective antagonist with pKB value of 8.9 in rabbit aorta. |
| PC-22446 |
ATR-127
β2/β3-adrenoceptor agonist
|
ATR-127 is a highly effective β2- and β3-adrenoceptors (ARs) agonist with pEC50 of 6.53 and 5.5 for rat β2-AR and mouse β3-AR, respectively. |
| PC-22239 |
SR59230A
β3AR antagonist
|
SR59230A is a potent, selective, and blood-brain barrier penetrating β3-adrenergic receptor antagonist with IC50 of 40, 408, and 648 nM for β3, β1, and β2 receptors, respectively. |
| PC-21223 |
ZD7114
beta-adrenoceptor agonist
|
ZD7114 (ICI D7114) is a potent, selective beta-adrenoceptor agonist, selectively stimulates brown fat and increases whole-body oxygen consumption. |
| PC-20987 |
Difluorophenyl Quinazoline
β2AR modulator
|
Difluorophenyl Quinazoline (DFPQ, AP-06-202) is a selective, biased, negative allosteric modulator of β-arrestin recruitment to the β2AR, without effect on on β2AR coupling to Gs. |
| PC-20986 |
L-771688
α1A adrenoceptor antagonist
|
L-771688 (L-771,688, SNAP 6383) is a potent and selective alpha1A (α1A)-adrenoceptor antagonist with binding Ki of 0.13 nM to α1-adrenoceptors in human prostate tissue. |
| PC-20804 |
Nebivolol hydrochloride
Beta adrenergic antagonist
|
Nebivolol hydrochloride (R 065824) is a beta adrenergic antagonist and shows direct vasodilator properties and adrenergic blocking characteristics. |
| PC-43177 |
Midodrine hydrochloride
|
Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension. |
| PC-43011 |
Atipamezole hydrochloride
|
Antipamezole (MPV-1248) is a potent, specific α2-adrenoceptor antagonist with Ki of 1.6 nM. |
| PC-42808 |
Asenapine maleate
|
Asenapine maleate (Org 5222) is a potent psychopharmacologic agent that shows high affinity for 5-HT, dopamine, histamine and adrenoceptors. |
| PC-62005 |
Milveterol hydrochloride
|
Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays, displays good β2/β1 selectivity (>300-fold). |
