| Cat. No. |
Product Name |
Information |
| PC-21121 |
SB-271046
5-HT6 antagonist
|
SB-271046 is a potent, selective and orally active 5-HT6 receptor antagonist, potently displaces [(3)H]-LSD and [(125)I]-SB-258585 from human 5-HT6 receptors recombinantly expressed in HeLa cells with pKi 8.92 and 9.09 respectively. |
| PC-20963 |
Pimavanserin
5-HT2A inverse agonist
|
Pimavanserin (ACP-103) is a potent, selective, orally active 5-HT2A receptor inverse agonist, competitively antagonizes the binding of [(3)H]ketanserin to heterologously expressed human 5-HT(2A) receptors with pKi of 9.3 in membranes and 9.70 in whole cells. |
| PC-49806 |
5-HT2A agonist (R)-70
5-HT2A agonist
|
5-HT2A agonist (R)-70 is a potent selective 5-HT2A receptor partial agonist with EC50 of 110 nM in calcium flux assays, and Ki value of 880 nM. |
| PC-49805 |
5-HT2A agonist (R)-69
5-HT2A agonist
|
5-HT2A agonist (R)-69 is a potent selective 5-HT2A receptor partial agonist with EC50 of 41 nM in calcium flux assays, and Ki value of 680 nM. |
| PC-49161 |
AS2030680
5-HT5A antagonist
|
AS2030680 is a potent, selective and brain-penetrating 5-HT5A receptor antagonist with Ki of 0.58, 1.1 and 2.6 nM against human, rat, mouse 5-HT5A receptors, respectively. |
| PC-49160 |
ASP5736
5-HT5A antagonist
|
AS5736 is a potent, selective and brain-penetrating 5-HT5A receptor antagonist with Ki of 3.6, 1.7 and 4.4 nM against human, rat, mouse 5-HT5A receptors, respectively. |
| PC-49159 |
AS2674723
5-HT5A antagonist
|
AS2674723 is a potent, selective and brain-penetrating 5-HT5A receptor antagonist with Ki of 0.75, 0.67 and 1.9 nM against human, rat, mouse 5-HT5A receptors, respectively. |
| PC-49006 |
LY344864
5-HT1F agonist
|
LY344864 is a potent, selective agonist of 5-HT1F receptor with Ki value of 6 nM, with little to no affinity for other serotonergic and non-serotonergic neuronal binding sites. |
| PC-47113 |
TZB-30878
5-HT1A agonist/5-HT3 antagonist
|
TZB-30878 is a potent, selective, orally bioavailable 5-HT1A agonist and 5-HT3 antagonist, selectively binds to human 5-HT1A and 5-HT) receptors with Kd values of 0.68 and 8.90 nM, respectively. |
| PC-47112 |
CSTI-300
5-HT3 agonist
|
CSTI-300 (SMP-100) is a potent, selective 5-HT3 receptor partial agonist with high affinity for human and rat 5-HT3 receptor (Ki=2.0 nM). |
| PC-38843 |
Ritanserin
5-HT2 antagonist
|
Ritanserin (R-55667) is a potent, selective and long-acting 5-HT2 receptor antagonist with Ki of 0.39 nM, shows anxiolytic effects. |
| PC-38717 |
UCSF678
5-HT5A agonist
|
UCSF678 is a potent, selective arrestin-biased partial agonist of 5-HT5A serotonin receptor with EC50 of 42 nM. |
