JZ-1201 | SERT/NET inhibitor, 5-HT1A agonist | Probechem Biochemicals

Chemical Structure : JZ-1201

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JZ-1201 (JZ1201)

货号: PC-26559Not For Human Use, Lab Use Only.

JZ-1201 is a selective serotonin (5-HT)/norepinephrine (NE) reuptake inhibitor and partial agonist of the 5-HT1A receptor, selectively binds to the SERT, NET, and 5-HT1A receptor with Ki values of 1.62 nM, 0.87 nM, and 0.22 nM, exerts antidepressant-like effects.

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生物&药学活性

JZ-1201 is a selective serotonin (5-HT)/norepinephrine (NE) reuptake inhibitor and partial agonist of the 5-HT1A receptor, selectively binds to the SERT, NET, and 5-HT1A receptor with Ki values of 1.62 nM, 0.87 nM, and 0.22 nM, exerts antidepressant-like effects.

物理化学性质&存储条件

分子量	454.97
分子式	C26H28ClFN2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-7-((1-(2-chloro-4-fluorophenyl)piperidin-4-yl)(cyclopentyl)methoxy)quinolin-2(1H)-one

参考文献

1. Gao H, et al. Naunyn Schmiedebergs Arch Pharmacol. 2026 Apr 15. doi: 10.1007/s00210-026-05333-6.

JZ-1201 (JZ1201)

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物理化学性质&存储条件

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JZ-1201 (JZ1201)

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