Cat. No. |
Product Name |
Information |
PC-45102 |
CC-115 hydrochloride
DNA-PK/mTOR inhibitor
|
CC-115 hydrochloride is a potent, dual inhibitor of mTOR and DNA-PK with IC50 of 21 nM and 13 nM, respectively. |
PC-42464 |
Rapamycin
mTOR inhibitor
|
Rapamycin (Sirolimus) is a macrolide compound that has potent immunosuppressive and antiproliferative properties by inhibiting mTOR (IC50=0.1 nM), induces autophagy. |
PC-24226 |
TMBIM6 inhibitor BIA
TMBIM6 inhibitor
|
TMBIM6 inhibitor BIA is a specific inhibitor of TMBIM6 (BAX inhibitor-1, BI-1), prevents TMBIM6 binding to mTORC2, decreases mTORC2 activity, also suppresses ER release of Ca2+ from TMBIM6, has broad anticancer activities. |
PC-62011 |
CIDD 0067106
|
CIDD 0067106 is a novel natural product-based diaryloxazole that potent and selective antiproliferative activities against androgen receptor-positive breast cancer cells (MDA-MB-453 cell GI50=0.8 uM). |