mTOR (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-60920	mTOR inhibitor 10 mTOR inhibitor	mTOR inhibitor 10 is a potent, selective mTOR inhibitor with biochemical IC50 of 21.7 nM for mTORC1, exhibits cellular potency against mTOR with IC50 of 5 nM.
PC-60555	NV-128 mTOR inhibitor	NV-128 (LY-303511) is a novel isoflavone derivative that inhibits mTOR and promotes caspase-independent cell death.
PC-60554	ME-344 mTOR inhibitor, HO-1 inhibitor	ME-344 (NV-344) is a novel mitochondrial and mTOR inhibitor with potent anti-cancer activity, inhibits leukemia cell lines with IC50 of 70-260 nM, also targets heme oxygenase 1 (HO-1) and disrupts redox homeostasis.
PC-60482	AZD3147 mTOR inhibitor	AZD3147 is a potent, selective dual mTORC1 and mTORC2 inhibitor with enzyme IC50 of 1.5 nM.
PC-60418	RapaLink-1 mTOR inhibitor	RapaLink-1 is a third-generation mTOR inhibitor that overcomes resistance to existing first- and second-generation inhibitors.
PC-60132	Temsirolimus mTOR inhibitor	Temsirolimus (CCI779, Torisel) is a rapamycin ester and mTOR inhibitor with biochemical IC50 of 1.74 uM.
PC-45649	Seco Rapamycin sodium salt	Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin that does not affect mTOR..
PC-45851	KU-0063794 mTOR inhibitor	KU-0063794 is a potent, specific, cell permeant inhibitor of mTOR with IC50 of 10 nM for both mTORC1 and mTORC2.
PC-42157	WYE-132 mTOR inhibitor	WYE-132 (WYE-125132) is a potent, specific, ATP-competitive and orally active mTOR inhibitor with IC50 of 0.19 nM.
PC-42608	PP242 mTOR inhibitor	Torkinib (PP242) is a potent, specific active-site inhibitor of mTOR with IC50 of 30 and 58 nM for mTORC1 and mTORC2, respectively.
PC-42576	AZD-8055 mTOR inhibitor	AZD-8055 is a potent, selective, ATP-competitive and orally bioavailable mTOR inhibitor with IC50 of 0.8 nM.
PC-45098	Onatasertib mTOR inhibitor	Onatasertib (CC-223, ATG-008) is a potent, selective, and orally bioavailable inhibitor of mTOR kinase with IC50 of 16 nM.

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