| Cat. No. |
Product Name |
Information |
| PC-21034 |
UBP141
GluN2C/2D antagonist
|
UBP141 is a selective GluN2C/2D-containing NMDA receptors antagonist with Kd values of 2.8 and 4.2 uM respecitvely, shows weaker activities against GluN2A and 2B (Kd=14.2 and 19.3 uM). |
| PC-21033 |
UBP791
GluN2C/2D antagonist
|
UBP791 is a subtype-selective competitive antagonist of GluN2C/2D-containing NMDA receptors with Ki of 80-90 nM, 50-fold selectivity over GluN2A and GluN2B. |
| PC-21032 |
UBP1700
GluN2C/2D antagonist
|
UBP1700 is a subtype-selective competitive antagonist of GluN2C/2D-containing NMDA receptors with Ki of 7-9 nM, 50-fold selectivity over GluN2A and GluN2B. |
| PC-21031 |
DQP-997-74
GluN2C/2D NAM
|
DQP-997-74 is a potent, selective GluN2C- and GluN2D-containing NMDARs negative allosteric modulator with IC50 of 0.35 and 0.13 uM, respectively, exhibits >100-fold over GluN2A- and GluN2B-containing receptors. |
| PC-21029 |
DQP-1105
GluN2C/2D antagonist
|
DQP-1105 is a selective GluN2C- and GluN2D-containing NMDARs antagonist with IC50 of 7.0 and 2.7 uM respectively, >50-fold selectivity over GluN2A- or GluN2B-containing receptors. |
| PC-43363 |
SDZ 220-581 hydrochloride
|
SDZ 220-581 is a potent, competitive NMDA receptor antagonist with pKi of 7.7, fully protects against maximal electroshock seizures (MES) at oral doses of 10 mg/kg in rats and in mice. . |
| PC-43362 |
SDZ 220-581 ammonium salt
|
SDZ 220-581 is a potent, competitive NMDA receptor antagonist with pKi of 7.7, fully protects against maximal electroshock seizures (MES) at oral doses of 10 mg/kg in rats and in mice. . |
| PC-61710 |
Irampanel hydrochloride
|
Irampanel (BIIR 561) is a combined antagonist of AMPA receptors (AMPAR) and voltage-dependent sodium channels. |
