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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-Memantine
Memantine

Chemical Structure : Memantine

CAS No.: 19982-08-2

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Memantine

货号: PC-26935Not For Human Use, Lab Use Only.

Memantine is an orally active, noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist with Ki of 0.19 uM for competing with [3H]MK-801 binding in membrane homogenates of postmortem human frontal cortex.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Memantine is an orally active, noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist with Ki of 0.19 uM for competing with [3H]MK-801 binding in membrane homogenates of postmortem human frontal cortex.

物理化学性质&存储条件

分子量 179.31
分子式 C12H21N
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-amino-3,5-dimethyl-adamantane

参考文献

1. Erdö SL, et al. Eur J Pharmacol. 1991 Jun 6;198(2-3):215-7.

2. Kornhuber J, et al. Eur J Pharmacol. 1991 Apr 25;206(4):297-300.

3. Seif el Nasr M, et al. Eur J Pharmacol. 1990 Aug 21;185(1):19-24.

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